The Center for Better Beginnings actively contributes to the understanding of birth defects and pregnancy outcomes by publishing articles in scientific journals detailing the findings of our research. We have published articles on topics that include but are not limited to:

Alcohol and Pregnancy

Jones KL, Chambers C. Biomarkers of fetal exposure to alcohol: identification of at-risk pregnancies. J Pediatr. 1998;133:316-8 .

Chambers CD, Jones KL. Is genotype important in predicting the fetal alcohol syndrome? Pediatrics. 2002;141:751-2.

Jones KL, Chambers CD, Hill LL, Hull AD, Riley EP. Alcohol use in pregnancy: inadequate recommendations for an increasing problem. BJOG. 2006;113(8):967-8.

Chambers CD, Kavteladze L, Joutchenko L, Bakhireva L, Jones KL. Alcohol consumption patterns among pregnant women in the Moscow region of the Russian Federation. Alcohol. 2006;38(3):133-7.

Jones KL, Robinson L, Bakhireva L, Marintcheva G, Storojev V, Strahova A, Sergeevskaya S, Budantseva S, Mattson S, Riley E, Chambers C. Accuracy of the diagnosis of fetal alcohol syndrome by pediatricians after specialized training. Pediatrics. 2006;118(6):e1734-8.

Jones KJ, Hoyme HE, Robinson LK, del Campo M, Manning MA, Prewitt L, Chambers CD. Fetal alcohol spectrum disorders: extending the range of structural defects. Am J Med Genet A. 2010;152A:2731-5. PMCID:PMC3143840

Chambers CD, Yevtushok L, Zymak-Zakutnya N, Korzhynskyy Y, Ostapchuk L, Akhmedzhanova D, Chan PR, Xu R, Wertelecki W. Prevalence and predictors of maternal alcohol consumption in 2 regions of Ukraine. Alcohol Clin Exp Res. 2014;38(4):1012-9.

Antidepressants and Pregnancy

Chambers CD, Johnson KA, Dick LM, Felix RJ, Jones KL. Birth outcomes in pregnant women taking fluoxetine. New Engl J Med. 1996;335:1010-5 .

Chambers CD1, Hernandez-Diaz S, Van Marter LJ, Werler MM, Louik C, Jones KL, Mitchell AA. Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med. 2006 Feb 9;354(6):579-87.

Chambers CD, Moses-Kolko E, Wisner KL. Antidepressant use in pregnancy: new concerns, old dilemmas. Expert Rev Neurother. 2007;7(7):761-4.

Chambers CD. Selective serotonin reuptake inhibitors and congenital malformations. BMJ. 2009;339:b3525.

Asthma and Pregnancy

Chambers C. Safety of asthma and allergy medications in pregnancy. Immunol Allergy Clin North Am. 2006;26:13-28.

Bakhireva LN, Schatz M, Jones KL, Chambers CD. Asthma control during pregnancy and the risk of preterm delivery or impaired fetal growth. Ann Allergy Asthma Immunol. 2008;101:137-43.

Autoimmune Diseases, Treatments, and Pregnancy

Chambers CD, Tutuncu ZN, Johnson D, Jones KL. Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data. Arthritis Res Ther. 2006;8(4):215.

Chambers CD, Johnson DL, Robinson LK, Braddock SR, Xu R, Lopez-Jimenez J, Mirrasoul N, Salas E, Luo YJ, Jin S, Jones KL, OTIS Collaborative Research Group. Birth outcomes in women who have taken leflunomide during pregnancy. Arthritis Rheum. 2010;65(5):1494-1503.

Cassina M, Johnson D, Robinson L, Braddock S, Xu R, Lopez-Jimenez J, Mirrasoul N, Salas E, Luo Y, Jones KL, Chambers CD; the Organization of Teratology Information Specialists Collaborative Research Group. Pregnancy outcome in women exposed to leflunomide before or during pregnancy. Arthritis and Rheum. 2012;64(7):2085-94.

Chambers CD, Johnson DL. Emerging data on the use of anti-tumor necrosis factor-alpha medications in pregnancy. Birth Defects Res A Clin Molec Teratol. 2012;94(8):607-11.

Miscellaneous Medication Exposures and Pregnancy

Chambers CD, Jones KL, Lammer EJ, Van Bennekom CM, Mitchell AA. Accutane-exposed pregnancies – California, 1999. MMWR. 2000;49:28-31 .

Jones KL, Johnson KA, Dick LM, Felix RJ, Kao KK, Chambers CD. Pregnancy outcomes after first trimester exposure to phentermine/fenfluramine. Teratology. 2002;65:125-30.

Medical Conditions and Pregnancy

Chambers CD, Jones KL. Risk for fetal death after fever in pregnancy. Lancet. 2002;360:1526.

Vaccines and Pregnancy

Chambers CD, Johnson D, Xu R, Luo Y, Louik C, Mitchell AA, Schatz M, Jones KL; OTIS Collaborative Research Group. Risks and safety of pandemic H1N1 influenza vaccine in pregnancy: birth defects, spontaneous abortion, preterm delivery, and small for gestational age infants. Vaccine. 2013;31(44):5026-32.

Dysmorphology and Teratology Miscellaneous Studies

Chambers CD, Castilla EE, Orioli I, Jones KL. Intrauterine growth restriction in like-sex twins discordant for structural defects. Birth Defects Res Part A Clin Mol Teratol. 2006;76(4):246-8.

Chambers CD, Chen BH, Kalla K, Jernigan L, Jones KL. Novel risk factor for gastroschisis: change in paternity. Am J Med Ge net. 2007;143(7):653-9.

Jones KL, Benirschke K, Chambers CD. Gastroschisis: etiology and developmental pathogenesis. Clin Genet. 2009;75(4):322-5.

Jones KL, Jones MC. 50 years ago in the J Pediatr: The no.18 trisomy syndrome. J Pediatr. 2012; 160(4):566.

Jones KL, Weiss LA, Hagey LR, Gonzalez V, Benirschke K, Chambers CD. Altered lipid metabolism in gastroschisis: a novel hypothesis.Am J Med Genet A. 2013;161A(8):1860-5.

Research Methodology

Chambers C. The role of teratology information services in screening for teratogenic exposures: challenges and opportunities. Am J Med Genet C Semin Med Genet. 2011;157C(3):195-200.

Chambers CD, Braddock SR, Briggs GG, Einarson A, Johnson YR, Miller RK, Polifka JE, Robinson LK, Stepanuk K, Jones KL. Post marketing surveillance for human teratogenicity: a model approach. Teratology. 2 001;64:252-61.

Chambers CD. Value of the small cohort study including a physical examination for minor structural defects in identifying new human teratogens. Congenit Anom (Kyoto). 2011;51(1):16-20

Comprehensive List of Publications

To view a complete list of publications from each of our faculty, click on the author’s name below:

Ken Lyons Jones

Tina Chambers

Miguel del Campo Casanelles

Kristin Palmsten

Diana Simmes